Do you want to contribute to top quality medical research?

We are recruiting a student for doctoral education. After a candidate is selected, an admission process commences. The candidate is admitted as a student once an individual study plan for the doctoral education has been approved by the departmental admission board.

For more information regarding doctoral (PhD) education, see: http://www.ki.se/doctoral.

The research group

The Department of Microbiology, Tumor and Cell Biology announces an opportunity to join the group of Professor Karlsson Hedestam as a PhD student in computational immunology. The group studies adaptive immunity and immunogenetics using a combination of wet lab and computational approaches. For more information, see http://ki.se/en/mtc/gunilla-karlsson-hedestam-group.

The doctoral student project and the duties of the doctoral student

B and T lymphocytes express highly polymorphic receptors encoded by gene segments that recombine in a combinatorial manner during lymphocyte development. By using next generation sequencing of expressed immune repertoires and computational analysis tools, variation in the genetic regions that encode these segments can be studied in-depth and in a high throughput manner. The group generates large amounts of adaptive immune receptor repertoire (AIRR) data in projects related to infection and autoimmunity. In collaboration with the Murrell lab, also at MTC, this PhD project will use existing tools and develop additional bioinformatic approaches for AIRR sequence analysis and apply to these sample collections.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

- Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

Previous experience with analysis of AIRR sequence data is required. Knowledge of tools used for germline immune gene inference is an advantage. Additionally, the individual must have experience with core bioinformatics algorithms (eg. Sequence alignment, Hidden Markov Models, dynamic programming, etc) and data structures (trees, graphs, etc), and have demonstrated experience writing code, including in Phyton, to process high-volume next-generation sequencing data. We are looking for a highly motivated and creative person. Excellent communication skills in written and spoken English are required.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.


Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

- A personal letter and a curriculum vitae
- Degree projects and previous publications, if any
- Any other documentation showing the desirable skills and personal qualities described above
- Documents certifying your general eligibility (see A above)
- Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

- Documented subject knowledge of relevance to the area of research
- Analytical skill
- Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.


Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.


Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone. For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

Want to make a difference? Join us and contribute to better health for all

Type of employment PhD placement
Contract type Full time
First day of employment According to agreement
Salary Monthly salary
Number of positions 1
Working hours 100
City Solna
County Stockholms län
Country Sweden
Reference number STÖD 2-1582/2021
Contact
  • Gunilla Karlsson Hedestam, gunilla.karlsson.hedestam@ki.se
Union representative
  • Henry Wölling, SEKO, henry.wolling@ki.se
  • Taher Darreh-Shori, SACO, taher.darreh-shori@ki.se
  • Carina Eklund, OFR, carina.eklund@ki.se
Published 26.Mar.2021
Last application date 09.Apr.2021 11:59 PM CET

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